Effect of Ag:Au nanoparticles prepared by plasma jet on breast cancer (MDA) cells line

Abstract

This work involved the synthesis of nanoparticles utilizing the plasma jet technology and the evaluation of their impact on a breast cancer cell line (MDA). The nanoparticle is created by coating silver with gold in various ratios (1:9, 2:8, and 3:7) and then compared to silver alone. Then the examination by UV-visible, X-Ray Diffraction, and Field Emission Scanning Electron Microscopy is done to show the effect of on both cancer cell lines and normal cell lines. After 48 hours, the cancer cell inhibition rate reached a maximum of 60% when the concentration is 100% for a ratio of 3:7. In contrast, the toxicity rate to normal cells is highest at 15.3% under the same conditions. The nanoparticle preparation method is simple, rapid, cost-effective, and efficient in suppressing breast cancer cells without harming normal cells.